tdh [2017-8-11 16:0:3]

L-threonine dehydrogenase

locus: BSU16990

pI: 6.06

mw: 36.84 kDa

protein length: 347 aa

gene length: 1041 bp

function: threonine utilization

product: L-threonine dehydrogenase

essential: no

ec: 1.1.1.103

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.8|Utilization of threonine/ glycine]

Gene

Coordinates: 1,770,461 → 1,771,504

The protein

Catalyzed reaction/ biological activity

• L-threonine + NAD⁺ = L-2-amino-3-oxobutanoate + NADH (according to Swiss-Prot)

Protein family

• zinc-containing alcohol dehydrogenase family (according to Swiss-Prot)

Structure

• [PDB|2DQ4] (from ''Thermus thermophilus'', 47% identity, 63% similarity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|8E64B62F15B92A2AACD68B913909100AE276D114|tdh]-[gene|1BC05699DEB3A16944FB8305F22976AED75805E8|kbl]
  description: [Pubmed|22383849]